The "Purple Rain" singer-songwriter is headlining the 20th annual Essence, a celebration of black music and culture being held July 3-6 in New Orleans.
Prince, who performed at Essence in 2004, also headlined this year's South By Southwest Music Festival in Austin, Texas. His newest single, "Screwdriver," debuted earlier this year. Still, Prince is best known for chart-topping hits like "1999," "Cool" and "Purple Rain."
Essence has been held every Independence Day weekend since 1995, when it marked the 25th anniversary of Essence magazine.
The event includes nightly concerts at the Louisiana Superdome and empowerment seminars during the day at a nearby convention center.
Organizers said the rest of the lineup will be announced later.